AlfaTech Big Book: Life Sciences

L I F E S C I E N C E S

BIOMARIN PHARMACEUTICAL GALL I EAST EXPANS ION (BGEX)

Novato, CA

Type: cGMP Manufacturing Size: 20,000 SF

AlfaTech’s services included management oversight of facilities operations for the manufacturing plant during facility validation. Scope included management of standard operating procedures, spare parts, training of new systems, turnover of systems and facility from contractor to BioMarin and plant engineering services.

BIOMARIN PHARMACEUTICAL* 95 Digital East Laboratory Build-out, Novato, CA

Type: R&D Laboratory

Engineering Design of HVAC, process systems and piping including process cooling water (PCW), clean in place (CIP) systems, deionized water (DI), water for injection (WFI), clean dry air (CDA) and plumbing for build out of shell space to new R&D laboratories.

BIOMARIN PHARMACEUTICAL* Novato, CA

BioMarin executed a utility yard expansion to accommodate additional capacity for lab and manufacturing facilities. The project included specification and conceptual design for addition of a 400-ton chiller to an existing 1000-ton system and 7,000 lb steam boiler to an existing 125 psig plant steam system. The scope also included design of a new enclosed two-story plant utility yard structure with architectural finishes to match the existing building. Challenges included design of new distribution piping to connect new equipment to the existing chilled water and plant steam systems, accommodation of existing equipment including emergency generator and water treatment systems as well as the facility’s loading dock.

* Completed by AlfaTech principal during previous employment