AlfaTech ISPE Life Sciences 2022

AL FATECH LOCAT IONS San Jose, California – HQ | San Francisco, California | Ventura, California | Monrovia, California | San Diego, California | Atlanta, Georgia

INNOVAT I VE I DEAS | SUSTAINABLE SOLUT IONS | INTEGRATED PARTNERSH I PS

Table of Contents

Life Science Project Experience

Firm Profile

01

Engineering Studio

02

03

Project Experience

04

Sustainability Studio

If you’re interested in more information on AlfaTech and how we can help you with an upcoming project, please contact:

Principal Terry Stelter Email: Terry.Stelter@atce.com Phone Number: (408) 487-1200

ALFATECH PROFILE

2022

Vela Tech Holdings, Inc. established for AlfaTech and other business units. Verity Commercial joins. Mumbai office opens.

2020

S&K Engineering of Monrovia and LFA Lighting of Ventura join our growing firm. Opens San Diego Office

COMPANY PROFILE

2019

Growth of leadership team. Further expansion into international markets with new and existing clients.

2018

Through RSBG: adds strength of 65+ offices throughout Europe, Asia, Middle East, and Africa.

AlfaTech was established in Silicon Valley in 1987 as a mechanical, electrical, and technology (low voltage, security, and A/V) design engineering firm. Responding to client needs, we grew our service offering to include architectural lighting design, sustainability, smart building, and project management services. In addition, we expanded into five California offices, including San Jose, San Francisco, Monrovia, Ventura, and San Diego. AlfaTech is gaining ground through organic, merger, and acquisition growth. Establishing Vela Tech company portfolio with parent company RSBG, our services reach the West Coast to the Midwest and the East Coast from partner offices in Seattle, Chicago, Reston, and Edison. We also have an international presence with offices throughout Europe, Asia, North Africa, and the Middle East. AlfaTech has a solid reputation forged by a corporate commitment to enduring client relationships and service excellence. We provide complete design, design-assist, and design/build project delivery services. Our project experience includes core and shell, tenant improvements, upgrades, repositioning, and restacks. Each AlfaTech project aims to achieve maximum energy performance, resource conservation, and pollution reduction, resulting in the highest energy savings and sustainability at all design phases while creating a balance of preservation, constructability, schedule, and budget. Given the dynamic nature of what we do, our AlfaTech teams are active listeners, and together with their focus on client and partner relations, are true team players.

2017

Expands offices in Los Angeles and Japan. Celebrates 30 Years Success!

2015

Develops partnerships in India, China, Hong Kong and Taiwan.

2014

Merges with Timmons Design. Expands San Francisco office to One Post Street Location

2012

Develops Architectural Lighting Design group. Creates Ireland and Thailand partnerships.

2010

Develops Sustainability / LEED and Energy Solutions groups.

2008

Ranked as one of the Top Five Engineering Firms in Silicon Valley

2006

Merges with MCT. AT-PD founded. Reports annual volume $150M

2003

Named one of the Top 100 Largest Private Companies in San Francisco.

2000

Named one of the Top 100 Fastest Growing Companies in Silicon Valley.

1996

Merges with S&H and MPL. Opens San Francisco office.

1989

Creation of an in-house Technology Group focused on voice, data systems, and overall technology

1987

Jeff Fini, PE, founds AlfaTech MEP Design in Silicon Valley

OUR LOCATIONS & SISTER COMPANIES ALFATECH is part of Vela Tech Holding portfolio of companies

ALFATECH + VELA TECH HOLDING

SISTER COMPANIES

ASIA Mumbai, India Pune, India Bangkok, Thailand Singapore Gandhingar, India New Dehli, India Dehradun, India Rajkot, India Visakhapatnam, India Dhaka, Bangladesh Brahmanbaria, Bangladesh

UNITED STATES San Francisco, California San Jose, California - HQ Monrovia, California Ventura, California San Diego, California Seattle, Washington

MIDDLE EAST Doha, Qatar Bagdad, Iraq Abu Dhabi, UAE Al Ain, UAE Madiant Zayad, UAE Dubai, UAE Riyadh, Saudi Aribia Jeddah, Saudi Arabia

EUROPE London, England

Warwickshire, England Saint-Cannat, France Essen, Germany Frankfurt, Germany Munich, Germany Bochum, Germany Berlin, Germany Hamburg, Germany Ribnitz-Damgarten, Germany Rostock, Germany Wiesbaden, Germany Stralsund, Germany Vienna, Austria Kornberg, Austria

Chicago, Illinois Reston, Virginia Edison, New Jersey

Amman, Jordan Istanbul, Turkey

NORTHERN AFRICA Cairo, Egypt

ALFATECH ENGINEERING

LABORATORIES Clinical QC BSL 1, 2 and 3 Flexible Labs

GENERAL BUILDING / CAMPUS SYSTEMS AND SPACES Site Electrical Distribution Backup Generation UPS HVAC Lighting and Lighting Controls BMS/EMS Central Plants Tank Farms and Utility Yards

PROCESS AND BUILDING UTILITY SYSTEMS WFI CIP and SIP Clean Steam Process Chilled Water RO/DI CDA Specialty Gases Lab Gases Solvent Systems Central Plants PLANT AND CLEAN AIR SYSTEMS Scrubbers Clean Rooms Explosion Relief HEPA Filtration Room Pressure Profiles and Cascade Exhaust Hoods and Dust Collection

PERMITTING AND REGULATORY COMPLIANCE FDA Inspection Readiness Support Air Permitting Support Code Analysis and Building Code Occupancy Issues Building Permit Administration and Support

cGMP COMPLIANT MANUFACTURING

FACILITIES Pilot Plants Clean Rooms Commercial Manufacturing Process Batching and Campaigning Areas Blending and Mixing Rooms Fill and Finish Wash Room Packaging and Labeling Isolation Technology Containment Facilities Gowning Rooms Production Equipment Specification Production Equipment Utility Hookup Warehouse and Material Handling

WASTE WATER AND HAZARDOUS WASTE TREATMENT Incineration

Truck Docks Warehouse Data Centers Corporate Office

Solids Removal Systems Waste Treatment Process Design Recycling Systems Heavy Metals Removal and Neutralization Reverse Osmosis and Ultra Filtration Biohazard Treatment and Detoxification

Electrical Distribution (480V to Low Voltage Systems) Technology Systems (Communication, AV, Security, WIFI)

Solutions for R&D, Pilot Plant and Commercial Manufacturing Facilities AlfaTech offers a full range of professional engineering services from concept creation to commissioning and validation, including feasibility studies, condition assessments, planning, design, program management and construction period services. Our experienced professionals are experts in Life Science Facility design and understand the difficult decisions facility owners make every day when choosing between economy and function. Our team has the experience and capabilities to address projects throughout our clients’ facilities from labs to manufacturing or corporate office and campus infrastructure. We have the capacity, experience and business structure that allows us to support a wide range of projects from the small consulting scope to ground-up campus projects.

This combination of resources and skills provides a strong value proposition, predicated on innovative solutions and disciplined cost, quality and schedule management.

Our Services Process Engineering Lab Planning and Design Master Planning Mechanical Engineering Electrical Engineering Structural Engineering Architectural Lighting LV, AV and Security Design Facility Condition Assessment

Site Selection Sustainability FDA and EU Compliance Consulting Strategic Partner Services Architectural Planning and Design Structural Engineering Process Controls Validation Site Civil Engineering

Process Engineering Expertise

• People & Material Flow

• Process Development

• Clean-in-Place (CIP)

• Process Flow Diagrams

• Equipment Specification

• Process Simulation

• Material Balances

• Process Utility Design

• Batch & Continuous Processing

• Sterilization-in-Place (SIP)

• Failure Mode and Effect Analysis • Long-lead time equipment procurement specification

• Piping & Instrumentation Diagrams

• Process Scale-up

Facility Types

Pharmaceutical Biotech Medical Devices Food & Beverage

Large-scale Manufacturing

Process Development / Small-scale Manufacturing

Research & Development

Pilot Plants

cGMP regulated facilities in Life Science and Food & Beverage sectors Utility Central Plant and Process / MEP Infrastructure

ALFATECH PROJECT EXPERIENCE

LIFE SCIENCES

AlfaTech provides design and engineering services to create the world’s most advanced research facilities. AlfaTech’s planners, designers, and engineers are highly experienced in working with the finest scientific minds to solve the world’s evolving challenges.

Freenome, 3000 & 3300 Marina

Brisbane, CA

TYPE: SIZE:

Tenant Improvement 335,439

Freenome is a biotechnology company with a comprehensive multiomics platform for cancer detection using a routine blood draw. AlfaTech is providing mechanical, electrical, process and plumbing engineering design and technology services for the relocation of their headquarters at 3000 and 3300 Marina Blvd in Brisbane, CA. The 335,439 SF Life Science and R&D campus has two buildings, one being 197,959 SF and the other being 137,480 SF. The buildings occupy 8 floors and are divided into 50% office and 50% R&D lab area.

ALFATECH EXPERIENCE

Longfellow Real Estate Partners

San Mateo, CA

TYPE: SIZE:

Due Diligence 240,000 SF

AlfaTech provided initial pre-acquisition due diligence for two buildings, 120,000 SF each, in San Mateo to determine the MEP scope of work to return the building to Life Science lab use.

AlfaTech is also providing the MEP design-build engineering services for conversion of the office buildings to Life Science lab use.

ALFATECH EXPERIENCE

Longfellow Real Estate Partners

San Francisco, CA

TYPE: SIZE:

Due Diligence, High-Rise 750,000 SF

The firm provided pre-acquisition due diligence for this 12-story, Class A 750,000 SF building at 1800 Owens which to determine the MEP scope of work to return the building to Life Science lab use.

ALFATECH EXPERIENCE

SC Johnson Lifestyle Brands

San Francisco, CA

TYPE: SIZE:

Tenant Improvement 45,030 SF

AlfaTech provided the mechanical, electrical, plumbing and fire production engineering design for the tenant improvements to the 4th floor (45,030 SF) at 631 Howard. Programing included conversion from office space to life science lab space including a new formulation lab, packaging lab, and fragrance lab as well as plumbing for an Objet WaterJet and anchoring for 3D printers and other equipment. AlfaTech also provided Value Engineering recommendations for the project.

ALFATECH EXPERIENCE

AbbVie (Abbott Biotherapeutics)

Redwood City, CA

TYPE: SIZE:

New Construction, Tenant Improvement 400,000 SF

AlfaTech was selected as a turnkey firm to design and build Abbott's 400,000 SF new headquarters campus. The facility now houses an Abbott spinoff company called AbbVie. This project includes a 4,000 SF raised floor data center, tenant improvement of offices, along with laboratory facilities, and vivarium (animal care facility). A pilot plant (cell culture and purification) was built on the first floor along with new laboratory facilities, offices, and service yard. AlfaTech was fully responsibly for programming, design and construction of this state-of-the-art campus for which the budget and schedule was guaranteed as a part of our highly successful single-source project delivery method.

ALFATECH EXPERIENCE

Gilead Sciences

Foster City, CA

TYPE: SIZE:

Tenant Improvement 500,000 SF

AlfaTech provided MEP and telecommunications design for Gilead’s campus consisting of 16 buildings including administrative a nd private offices, pharmaceutical development processing suites, pilot plants and cGMP therapeutic manufacturing / production areas. The firm also provided MEP engineering design services for Gilead’s 35,000 SF pilot plant on the Foster City campus as part o f a previous project.

New Systems include: • Process Vacuum System • Nitrogen System • Process Compressed Air System • Cooling System • Dust Collection System

• Emergency Power System • Distribution System • Class II Hazardous Locations (Granulation and Drying, Milling and Blending, Tablet Coating, Tablet Compression, Weigh Room)

• Air Shower System • USP Water System • RO/DI Water System • Domestic Water System • N2 Gas System • Process Waste System • Building Service System

• Exhaust System • System Controls

ALFATECH EXPERIENCE

Genentech

South San Francisco, CA

TYPE: SIZE:

New Construction, Design-Build 100,000 SF

AlfaTech provided a new $1.1 million, 2-story facility for animal research labs and support areas. The mechanical design features double-duct, double-fan, constant volume mixing boxes with HEPA filtration. In addition, the firm provided full facility design services for Genentech’s Vacaville campus under a Master Services Agreement. This work encompasses office space, laboratory and cGMP manufacturing.

ALFATECH EXPERIENCE

Genentech*

South San Francisco, CA

TYPE:

Tenant Improvement

Small Portfolio Program ($10 mm and less construction value). Supported Genentech’s Small Project Portfolio program for the pharmaceutical research and manufacturing company’s South San Francisco Campus. Provided Architecture and Engineering planning, design and construction support for a wide variety of facility projects including research labs, GMP cold room upgrades, building condition assessment and upgrades, waste stream compliance and utility systems. Utility systems include electrical infrastructure, steam, compressed air, exhaust, fire suppression, domestic water, sanitary sewer, chilled water and plant gases.

ALFATECH EXPERIENCE

* Completed by AlfaTech principal during previous employment

Genencor* Palo Alto, CA

TYPE: SIZE:

Tenant Improvement 77,500 SF

This lab expansion project was an expansion of the food-grade fermentation, large scale recovery, small scale recovery, and granulation lab suites/processes. The 20,000 SF expansion included two new 2,000L fermentation vessels and associate holding tanks, four new 1,500L recovery vessels, an entirely new 14L small scale recovery suite with Millipore, Buchner, and Microfiltration processing, and spray dryer process addition to Granulation Suite/Process. Provided complete mechanical, electrical, plumbing, and process piping design including coordination with process equipment vendors. Collaboration with scientists to develop custom Millipore Bench and Buchner walk-in hoods with special consideration for enzyme aerosol mitigation. Process and utility piping design to support the new process vessels and equipment including Steam & Condensate, Compressed Dry Air, Hot and Cold Glycol, Heating Hot Water, DI Water, Industrial Cold & Hot Water, Process Vacuum, and Contained Drains.

ALFATECH EXPERIENCE

* Completed by AlfaTech principal during previous employment

*Confidential Client, Textured Vegetable & Fiber Spin Pilot Labs

Redwood City, CA

TYPE:

Tenant Improvement

This confidential client is on a mission to be the future of sustainable food by giving people options to reduce their carbon footprint by consuming their plant-based meat products. This project retrofitted an existing building into labs for textured vegetable protein extrusion processing line and fiber spin aqueous based process line. Multiple process equipment vendors were evaluated for viability of the clients changing processing needs throughout the duration of the process. Provided MEP design for the cGMP equivalent labs designed to food grade standards. New systems included food grade air handling, solvent bunker, dust collection system, food grade steam, RO water, process cooling water, compressed air, CIP/COP, wastewater treatment, building service system and lighting.

ALFATECH EXPERIENCE

* Completed by AlfaTech principal during previous employment

Beyond Meat Headquarters

El Segundo, CA

TYPE: SIZE:

Tenant Improvement 250,000 SF

AlfaTech is providing mechanical, electrical, plumbing, fire protection and process piping engineering design services for the relocation to the new headquarters for Beyond Meat into a 2-story building. Project includes complete demolition of the interior and will consist of a 143,000 SF R&D, Lab Space, Test Kitchens and Refrigerated Storage and 107,000 SF office space in a phased construction. Project included the design of the “house” high pressure steam system (100 PSIG), including steam boilers, a deaerator/boiler feedwater system, a blowdown tank, a flash tank, chemical treatment, steam system controls, a steam distribution system (including expansion joints), steam trapping, condensate distribution, condensate pumps, condensate coolers, etc. Also included was a “clean - steam” generator and a clean -steam distribution system.

ALFATECH EXPERIENCE

Niagara Bottling, LLC

Diamond Bar, CA

TYPE: SIZE:

Tenant Improvements 382,000 SF

Niagara Bottling, LLC is a family-owned manufacturer of bottled water and soft drinks based in Ontario, California. They produce private label bottled water for a number of companies including Wal-Mart and Costco. As of 2017 Niagara was the largest supplier of private label bottled water in America. Niagara looked towards creating a unique experience for their staff at their new Corporate Headquarters Campus. The scope of work comprised of a core and shell renovation and simultaneous TI of Bldg. 1 (182,000SF), R&D and QA Lab in Bldg. 2 (20,000 SF), site improvements (80,000 SF), 500kW Campus E-Power System and lighting, power and EV charging renovations to a (176,000 SF) parking structure. The Lab comprised of Analytical Rooms, Micro Rooms, Q/A Lab, Sample Storage Rooms, Cold Storage Rooms, R&D Lab and office space. The main office building included a full-service staff cafeteria with waste composting system, Executive Offices, Private offices, Tasting Lounge/Kitchen, Conference rooms, Open Office Space, 3 Story main reception lobby, flex spaces, games rooms, (6) IDF rooms and a Main Server/MDF room.

ALFATECH EXPERIENCE

Confidential Biotechnology Research Company

Redwood City and San Diego, CA

TYPE: SIZE:

Tenant Improvement, New Ground-Up 450,000 SF

This confidential biotechnology research company’s goal is to develop life extension therapies that can halt or reverse the h uman aging process.

Redwood City, CA AlfaTech is providing mechanical, electrical, plumbing, process and fire protection engineering design services to the confidential client's corporate headquarters in Redwood City, CA. The headquarters will be comprised of 3 buildings of office conversion to lab/office, totaling 150,000 SF and one expansion building at 50,000 SF. Lab spaces for all buildings are mostly biology laboratories with some chemistry. The lab to office ratio will be 50/50, with some additional corporate office and meeting areas. San Diego, CA AlfaTech is providing mechanical, electrical, plumbing, process and fire protection engineering design services to the confidential client's campus in San Diego, CA. The 2 new ground-up buildings total 300,000 SF and are mostly lab spaces for chemistry and biology. The lab to office ratio will be 50/50 for most of the buildings. AlfaTech is also designing the campus central plant and the client’s vivarium

ALFATECH EXPERIENCE

Amgen, Buildings 31 And 42

Thousand Oaks, CA

TYPE: SIZE:

Tenant Improvement Building 31, 10,000 SF; Building 42, 15,000 SF

Amgen is a global biotechnology company that discovers, develops, manufactures and markets cost-effective human therapeutics based on advances in cellular and molecular biology. A large-scale dispensing suite was added to Building 31 and Building 42 was a new cGMP raw material receiving facility. On Building 31, AlfaTech provided mechanical, electrical, plumbing, support utility design, specifications, and specialized equipment sourcing for construction of cGMP raw material dispensing suites within an existing warehouse and distribution facility. Building 42 was programmed and designed for cGMP raw material receiving and support for Building 23, a clinical trial manufacturing facility. Process engineering design included liquid caustic solution receiving, storage and transfer systems, and fresh and waste glycerol streams storage and transfer systems.

ALFATECH EXPERIENCE

Alza

Various Bay Area Sites

TYPE: SIZE:

Tenant Improvement 1,000,000+ SF

AlfaTech and AlfaTech team members have provided design services for various Bay Area sites listed above.

Projects: Vacaville cGMP Facilities: • Original Manufacturing Building • Aqueous Tablet Coater • Fluid Bed Dryer • High Shear Granulation • Pharmaceutical Processing Area • Tablet Coating Process • Methylene Chloride Distribution

Mountain View Facilities: • Buildings M2 & M3 Biocenter • M1 Pilot Plant & Research Center

Palo Alto Facility: • Buildings M8 & M9 • Underground Tanks

ALFATECH EXPERIENCE

Terasaki Research Group

West Los Angeles, CA

Tenant Improvement

TYPE:

AlfaTech is providing engineering design services for this project requiring an extensive renovation/transformation of an existing veterinary facility to create a new Vivarium suite within an animal research facility. The project included autoclave cage vivarium cage washers, bio-safety cabinets, procedure rooms, animal handling areas, Rheometer. The facility was designed in accordance with the AAALAC. guidelines. The existing electrical generator and vacuum systems within the veterinary clinic were repurposed and modified as necessary to suit. New HVAC equipment was added to isolate specific areas of the building and increase air change rates within the space. The existing surgery rooms were renovated to procedure rooms. The existing labs were renovated and re-purposed to match the programmatic requirements of the new tenant.

ALFATECH EXPERIENCE

The Jackson Laboratory West

West Sacramento, CA

TYPE: SIZE:

Tenant Improvement 91,000 SF

AlfaTech provided MEP design services for interior improvements to an existing tilt-up concrete warehouse, as well as an expansion into an existing facility. The new use of this space includes West Coast regional offices, animal vivarium, wash/sterilization facilities, various research laboratories, animal shipping/staging/support spaces, mechanical yard, and parking.

ALFATECH EXPERIENCE

Buck Institute Stem Cell Research Lab

Novato, CA

TYPE: SIZE:

Tenant Improvement 60,000 SF

AlfaTech provided project management, as well as mechanical and electrical engineering services for this project. Systems include the addition of a ground coupled geothermal system, which provides heating and cooling to the new addition and the existing 60,000 SF lab facility. Geothermal ground water at 61 degrees will be used to condition lab fume hood make up air, freeing up 300 tons of cooling from the existing central plant. The additional chilled water tonnage will be used for the new addition. The new geothermal system will provide all cooling & heating for the existing & new 60,000 SF lab building, and “no additional tonnage” will be required for the existing central plant. The geothermal system will also save 7,500.000 gallons of water a year from being evaporated via the existing (now decommissioned) cooling towers.

ALFATECH EXPERIENCE

Jazz Pharmaceuticals

Palo Alto, CA

TYPE: SIZE:

Tenant Improvement 98,000 SF

AlfaTech provided the mechanical, plumbing, fire protection and electrical engineering design for this project which consisted of tenant improvements of this two-story R&D building in Stanford Research Park. Programming featured multiple breakrooms, private and open offices, conference rooms, IDF/MDF rooms and a high-end multitenant lobby. Additionally, project includes a 2,000 SF multi-purpose room with a motorized skyfold partition and high-tech video array wall.

Completed: February 2019

ALFATECH EXPERIENCE

Janssen Pharmaceuticals*

Vacaville, CA

TYPE:

Tenant Improvement

Janssen Pharmaceuticals operates a manufacturing site which was originally constructed in 1985. The HVAC design strategy originally employed consisted of installation of a dedicated HVAC systems for each separate space including each manufacturing suite, clean corridors, QC labs, washrooms, warehousing and administrative spaces. Between 2012 and 2019, Janssen embarked on a multi-year program to replace aging equipment. The effort included developing multiple options for consolidation of systems for cost and space efficiency while ensuring proper air distribution and balancing across the highly diverse environments in the building. Protecting again cross contamination and release of toxic chemicals was a top priority. The program also included goals for energy efficiency achieved by specifying highly efficient units, reviewing and revising required air changes and improving system monitoring and control.

ALFATECH EXPERIENCE

* Completed by AlfaTech principal during previous employment

Janssen Pharmaceuticals*

Vacaville, CA

TYPE:

Tenant Improvement

Numerous upgrade and expansion projects were executed throughout all aspects of the facility including labs, manufacturing process and HVAC systems and building utility upgrades, manufacturing clean room projects, site infrastructure and utilities and administrative tenant improvements. Projects included: • Multi-year plantwide HVAC system renovation and replacement to modernize the plant’s clean room HVAC systems and to meet cGMP requirements. • Process Dust Collection System collecting hazardous dust produced pharmaceutical product manufacturing. • Manufacturing Suite projects to accommodate new products and processes including suite workflow layout, utility system design (electrical, O2, AOF, N2, chilled water, clean steam, etc.), waste streams, Architectural improvements. • Regenerative Thermal Oxidizer • Manufacturing Equipment Safety Upgrades to meet J&J Corporate safety standards • Raw Materials Warehousing and Lab • 1MW Solar Farm Condition Assessment and Upgrades • Manufacturing Washrooms • QC Labs

• Code Studies • Data Center

ALFATECH EXPERIENCE

* Completed by AlfaTech principal during previous employment

BioMarin Pharmaceutical

Novato, CA

TYPE: SIZE:

Management Oversite 20,000 SF

AlfaTech’s services included management oversight of facilities operations for the manufacturing plant during facility validation. Scope included management of standard operating procedures, spare parts, training of new systems, turnover of systems and facility from contractor to BioMarin and plant engineering services.

ALFATECH EXPERIENCE

Nektar Pharmaceuticals

San Carlos, CA

Type: Size:

Data Center Consolidation 4,000 SF

AlfaTech provided technology design services for the consolidation of the central data center, which will occupy approximately 4,000 SF in a currently unoccupied space for Building 3. The data center was designed to provide higher availability and growth capacity for current demand and future growth including 80kW APC, UPS frame with initial 40kW of UPS power, (2) 15-ton chilled-water system CRAC units, (21) seismic isolation base and structured cabling system. Technology design included structured cabling for the data center, data network implementation, coordination of Telco facilities, security system design for card access and video surveillance, and PA/paging system.

Technology Design Services • Low Voltage • Security

ALFATECH EXPERIENCE

QuVa Pharma Sugar Land, TX

TYPE: SIZE:

Tenant Improvement 50,000 SF

QuVa Pharma, Inc. is a nationally recognized company emerging as the leading industry 503B platform and partner of choice for compliance-oriented healthcare facilities looking to ensure a quality, safe and consistent supply of medications. The Company offers a broad portfolio of products across Pain Management, Anti-infective, OR Syringes, Labor and Delivery therapeutic areas amongst others, all of which are released only once sterility and potency testing is successfully complete, and with validation supporting appropriate BUD. The project entailed design of a 50,000 SF storage and distribution warehouse expansion within their existing Sugarland location for compound ingredients. Our scope of engineering services included lighting, power distribution and HVAC.

ALFATECH EXPERIENCE

Confidential Life Sciences Campus Repositioning

Los Angeles, CA

TYPE: SIZE:

Tenant Improvement 180,000 SF

AlfaTech provided MEP engineering design services for this project with scope encompassing the conversion of 4 office buildings, totaling over 180,000 SF, into life science incubator labs, office space and cGMP space.

ALFATECH EXPERIENCE

UCLA Terasaki Life Sciences Building*

Los Angeles, CA

TYPE: SIZE: ACCREDITATION:

New Building 175,000 SF

LEED Silver

Terasaki Life Sciences Building features two wings with laboratories, offices, scholarly activity space, and building support spaces on five floors plus a basement vivarium. The 175,000 SF structure is supported by a cast-in-place concrete frame with flat-slab floor decks. This building, is the new home of the Biological Sciences Department. A stated goal of the UCLA Terasaki Life Sciences Building Detailed Project Program is to “provide flexible facilities that anticipate changing future needs.” To help meet thi s goal, the building was designed with large, open laboratory spaces to allow multiple scientists to work in shared laboratories, uninterrupted by doors or walls. Each rectangular wing houses an efficient pattern of laboratory, support and office space of five above ground levels. The building’s concrete frame eliminates 10 ft in height, as compared to the common structural steel alternative and provides inherent vibration control.

The vivarium on the lower level includes holding rooms for rodents, birds, fish and other small animal species.

ALFATECH EXPERIENCE

* Completed by AlfaTech principal during previous employment

Stanford University, Clark Center

Stanford, CA

TYPE: SIZE:

Peer Review, New Construction 146,000 SF

The 3-story, James H. Clark Center for Biomedical Engineering and Science is strategically located at the heart of Stanford's Palo Alto campus. The Clark Center houses the Bio-X programme and fosters an unprecedented degree of collaboration among scientists from different disciplines to meet some of the most pressing scientific and medical challenges. The project consisted of three wings of laboratories that frame an open courtyard overlooked by balconies and includes a full-scale kitchen and server with 200-seat dining area, a 150-seat auditorium, and classrooms. This facility is open and flexible with laboratory layouts that can be reconfigured at will. The research space houses more than 450 scientists, technicians and faculty in biology, biochemical, biophysical, biocomputational, bioengineering, and bio neurology disciplines. The firm was responsible for the design of the HVAC, fume exhaust, building automation, and peer review of the plumbing/process piping systems.

ALFATECH EXPERIENCE

Soka University Of America

Aliso Viejo, CA

TYPE: SIZE: ACCREDIATION:

New Construction 200,000 SF

LEED Gold anticipated

The firm provided mechanical, electrical, and plumbing engineering design services for this university campus expansion project for Soka University which consists of two buildings. The 4-story, 91,370 SF Marie and Pierre Curie Hall (STEM building) features 19 labs, three classrooms, 26 faculty and administrative offices, 11 conference rooms and a 100-seat auditorium alongside open collaborative spaces and student workstations throughout the facility. Core lab facilities, including an aquatics lab, scanning electron microscopy (SEM) and transmission electron microscopy (TEM), accommodate advanced research and help recruit new faculty. The building’s instructional lab modules allow for interactive teaching and hands -on learning in this open, flexible, interactive and sustainable building to support the new life sciences concentration for undergraduate students interested in biology, biomedical research, biotechnology, public health and medicine (pre-med). The Resident Housing are twin, 4- story, 52,470 SF buildings which anchor the university’s southwest border. Each hall contains 50 housing units (made up of single- and double – bedroom dormitories), meeting and social spaces, a kitchen and 24-hour study rooms with a covered walkway connecting the buildings.

Both proposed projects were designed to accommodate a LEED Gold Building Certification.

ALFATECH EXPERIENCE

University of San Francisco, Center for Science and Innovation

San Francisco, CA

TYPE: SIZE: ACCREDITATION:

New Construction 61,610 SF

LEED Gold

For the University of San Francisco, this 61,610 SF, five-level John Lo Schiavo, S.J. Situated in the center of campus it is a focus of student life and the primarily underground building design allowed for multi-level outdoor classrooms. Center for Science and Innovation, near the middle of the campus off Masonic Avenue. This building houses 17 wet and dry teaching/computational labs, classrooms, support spaces and offices and serves more than 6,000 students required to take one science and math course during their undergraduate time at USF. The building is the first constructed to meet LEED Gold standards at USF and features floor-to-ceiling windows, smart technology that opens and closes windows automatically for temperature, a 28,000-gallon cistern tank to collect rainwater for reuse, and indigenous Northern California landscaping.

ALFATECH EXPERIENCE

Compton Community College, Allied Health Building

Compton, CA

TYPE: SIZE:

Tenant Improvement 20,350 SF

The firm provided mechanical, electrical and plumbing engineering services for the state-of-the-art Allied Health Building at Compton College which houses the Nursing and Child Development programs. The building simulated a modern hospital environment and features hi-tech classrooms, one lecture hall, one simulation lab, four health science labs, 11 faculty offices and an office for the dean of student learning, a computer lab, shared group study areas, restroom facilities, faculty and staff kitchen/lounge and a student lounge. The building also has wireless access throughout and “smart” classroom technology.

ALFATECH EXPERIENCE

Antelope Valley College, Health & Science Center

Lancaster, CA

TYPE: SIZE :

New Construction 106,000 SF

This project consists of a new science laboratory and office complex of 106,000 SF located in Lancaster, California. The project includes 44,706 SF of laboratory and classroom space to support the biology, botany, microbiology, anatomy, physiology, physics, chemistry, astronomy, geology, anthropology, and geography departments. Another 21,000 SF devoted to Health Sciences programs including nursing, emergency medical services, surgical, cardiovascular and radiologic technology. Special features of the building include an 80-seat planetarium, Live Animal Room, Cadaver Room, a surgery demonstration lab and outdoor botany greenhouse. The remainder of the building includes 10,000 SF of classroom space, faculty offices, computer lab and a café/dining area. The building has a very unique shape and a very large footprint. It is also in the relatively harsh high desert area of Southern California which presents HVAC design issues among others. Due to the nature of chemicals involved in the laboratories, and high desert winds, a sophisticated wind tunnel test was performed to assure proper exhaust air location and treatment.

ALFATECH EXPERIENCE

El Camino College, Math, Business & Allied Health Building

Torrance, CA

105,000 SF SIZE: Tenant Improvement TYPE:

The firm provided complete mechanical, plumbing, fire protection, and electrical engineering consulting services for this project. The building is 105,000 SF with two floors above grade and a basement. The building will be completely renovated. Once complete, the building will house the main technology server array in a state-of-the-art data room complete with a dedicated chiller system utilizing hot and cold aisles within the room and new UPS systems and emergency generators for redundant backup. The UPS systems utilize N+1 technology. In addition, the building has an observatory on the roof. The HVAC design includes sophisticated isolation techniques to prevent vibration transmission to the extremely sensitive telescopes. The budget for the project is $40 million.

ALFATECH EXPERIENCE

Whittier College, Science & Learning Center

Whittier, CA

TYPE: SIZE:

Tenant Improvement 88,000 SF

This project was for complete renovation of the 1966 Stauffer Science Building at Whittier College and included seismic and accessibility upgrades, as well as new utility infrastructure and equipment. The long, raised-box form of the existing building was re-appropriated to create a more eye- catching exterior and improve the building’s relationship to the campus. Facing the campus quad, a nearly continuous glass facade is interrupted by terracotta pop-outs that serve as cross-disciplinary break- out alcoves. Building consists of Labs and classrooms, all which have been reconfigured featuring at least one glass wall, revealing student endeavors. Open study spaces are located throughout the building creating spaces for students to have meaningful interactions beyond the classroom. There is a two-story lobby with a staircase in the shape of a DNA helix providing a route up to the campus proper and a fifth- floor ‘penthouse’ providing inspiring views, unique classroom environments, and dedicated terrace space for the astronomy program’s telescopes The mechanical for the project consisted of a chilled water system with hot water reheat and custom air-handling units with variable frequency drives for a variable air volume (VAV) system. In addition, VAV fume hood exhaust systems with demand response were provided for maximum energy efficiency.

ALFATECH EXPERIENCE

California State University, Northridge, Science Buildings 3 & 4

Los Angeles, CA

TYPE: SIZE:

Tenant Improvement 75,000 SF

The project consisted primarily of retrofit of mechanical systems for two science buildings of nearly 75,000 SF. The buildings are mostly science classrooms of which numerous classrooms had several laboratory fume hoods. The buildings were under extreme negative air pressures resulting in adverse interior conditions, issues with doors opening and closing, and posing potential hazards. CSUN believed the proper solution was going to be additional make up air handling units. Such a solution would have been costly, disruptive, and operationally expensive. S&K studied existing plans and operational characteristics, and our findings were that make up air capacity was more than adequate, but it was not being controlled or operated correctly. Further investigation determined that the existing pneumatic control systems had been seriously damaged by the 1994 Northridge earthquake. The most cost effective solution was to install a new Direct Digital Control (DDC) system. S&K designed the new DDC system, and the problems were solved. In addition to resolving the pressurization problems, the new DDC system also increased occupant comfort and realized substantial energy savings.

ALFATECH EXPERIENCE

ALFATECH SUSTAINABLITY

SUSTAINABILITY STUDIO AlfaTech’s Sustainability Studio provides sustainable design solutions for prioritizing energy, water, and air quality. Our team brings deep MEP engineering expertise with digital skills. Our Sustainability Studio is a team of in-house experts whose purpose is to develop the most highly sustainable design strategies for each project. This multidisciplinary team assesses and designs projects with an integrated approach. Working with owners, architects, and other stakeholders, we examine every project with a comprehensive, systematic approach to map key programming targets. We establish project sustainability goals and collaboratively prioritize energy, water, and air quality requirements. We explore the latest system technologies and identify concepts most suitable to project applications. We perform life-cycle analysis, system simulations, and models that are utilized for validation. We review proposed system concepts with the project team to determine impacts and financial benefits in the earliest design stages.

AlfaTech goes beyond engineering – our suite of energy, water, and sustainability assessment services creates projects that benefit the triple bottom line – people, planet, and profit.

DESIGN APPROACH

AlfaTech maintains a commitment to sustainable design on every project. At the onset of a new project, our Sustainability Studio tea works with the client and the architect to establish and benchmark the project’s sustainability goals. Once these goals are set, we explore the latest system technologies, identify project-specific strategies available, and determine the most suited concepts to the project application. We provide preliminary studies of these systems, further validating the application. Together with the rest of the project team, we look at each system concept to determine the project impacts and financial benefits in the early stages of design.

SUSTAINABILITY IS A CORNERSTONE OF OUR PRACTICE

We follow a holistic approach to meet project expectations in all dimensions. Providing sustainable design is an achievement if it is also functional. Increasing efficiency is realistic when it is applicable. Meeting the project budget is possible when the design is constructible.

Lucas Museum of Narrative Arts

Uber Mission Bay

We take pride in our design and ensure that the following principles are aligned in our approach to every project:

Environmental impacts, carbon footprint reduction

Greenhouse Gases and Carbon

Imbalance between energy resource and energy use

Interstate or local differences

The water and energy nexus

Waste and ecology

OUR TRACK RECORD

LEED-ACCREDITED PROFESSIONALS

AlfaTech has over 30 employees that are currently USGBC LEED-Accredited professional with several staff members slated to take the test soon.

AlfaTech has experience working with the following:

Photovoltaic Power Generation

Geothermal Water-Source Mechanical System

Enthalpy Wheel Energy Recovery

Non-Chemical Water Treatment

Highly Efficient Plumbing Fixtures

Solar Thermal Systems

Lab/ Hospital Energy Recovery System, including Run Around coil

Underfloor Air Distribution System

Passive Natural Ventilation.

ENGINEERING STUDIO AlfaTech’s Engineering Services is the apex supplier of high-quality, professional engineering services that help buildings thrive. We partner with clients to turn their visions into a tangible reality. As one of the leading MEP consultants in the Western U.S., AlfaTech strives to improve the life of hundreds of thousands of Americans every day through the buildings we design. Coining the expression “Innovation & Excellence,” AlfaTech is the apex supplier of high -quality, professional engineering services that help buildings thrive. AlfaTech partners with ambitious clients to turn visions into reality. To us, conscious design elements are indispensable in meeting the escalating expectations emerging within vibrant and diverse typologies. We believe the highest-efficiency buildings transpire from mirroring the sustainable features inherent to the world around us. Propelling cutting-edge solutions requires a thoughtful design that can interact with the physical environment. Elements like smart buildings, reduced reheat, and synergies before waste initiate perpetual savings. Eager to do our part, we pride ourselves on designing state-of-the-art facilities that reach unprecedented levels of integration. We think that sustainable design is more than just a phrase. It is a perspective. We are committed to rock-solid partnerships with our clients by delivering on our promise always to excel.

OCCUPANCY

DESIGN

CONSTRUCTION

END OF USE

SUSTAINABLITY

PROCESS ENGINEERING DESIGN

MECHANICAL ENGINEERING DESIGN

ELECTRICAL ENGINEERING DESIGN

ARCHITECTURAL LIGHTING DESIGN

TECHNOLOGY

COMMISSIONING / ENERGY SOLUTIONS

RETRO COMMISSIONING

LIFE OF A BUILDING

NET ZERO Delta Products Headquarters, Fremont, CA PG&E, 77 Beale, San Francisco, CA

LEED GOLD (partial list) 300 Grant Avenue, San Francisco, CA Visa, 385 Sherman Ave, Palo Alto, CA Uber, Mission Bay 3 & 4, San Francisco, CA

Soka University, Aliso Viejo, CA Mission College, Santa Clara, CA College of Marin, Kentfield, CA Ohlone College, Fremont, CA

Adobe Data Center, Hillsboro, OR Adobe NA1 Data Center (Phase 2) Digital Realty, Santa Clara, CA Equinix, SV5, San Jose, CA

LIVING BUILDING CHALLENGE Google 237 Moffett Park Drive, Mountain View, CA

Facebook, Forth Worth, TX Facebook, Prineville, OR CoreSite, Santa Clara, CA Pathline, Sunnyvale, CA PG&E, 77 Beale Street, San Francisco, CA Synopsys Pathline HQ, Sunnyvale, CA Maxim Integrated Circuits, San Jose, CA eBay, Building 17, San Jose, CA

LEED PLATINUM Uber, Mission Bay 1 & 2, San Francisco, CA LinkedIn, 222 2nd Street, San Francisco, CA 23andMe Headquarters, Sunnyvale, CA VMWare Data Center, Wenatchee, WA Confidential Data Center | F, Lulea, Sweden Confidential Client | AC, Cupertino, CA Delta Products Headquarters, Fremont, CA Lucas Museum of Narrative Arts, Los Angeles, CA Ohlone College, Fremont, CA Berkeley YMCA Teen Center, Berkeley, CA UC Davis, Graduate School of Management & Gallagher Hall

Intuit, Mountain View, CA Intuit, Mountain View, CA Charles Schwab, Various Locations Symantec, Tucson, AZ Symantec, Mountain View, CA Bently Heritage Distillery, Creamery Building, Minden, NV Bently Heritage Distillery, Mill Building, Minden, NV USF, John Lo Schiavo Center for Science & Innovation Bellarmine College Prep High School Sobrato Ctr., San Jose, CA San Francisco Friends School, San Francisco, CA San Jose USD, Broadway High School, San Jose, CA

San Jose, California – HQ Elizabeth Monti, MBA Sr. Principal, Corporate Business Development 1321 Ridder Park Drive, No. 50

Monrovia, California Diarmuid Hartley Managing Partner

421 E Huntington Drive Monrovia, CA 91016 P: +1 213.212.9860 E: diarmuid.hartley@atce.com

San Jose, CA 95131 P: +1 408.487.1200 E: elizabeth.monti@atce.com

San Francisco, California Elizabeth Monti, MBA Sr. Principal, Corporate Business Development

Monrovia, California Kevin Keyfauver, PE, LEED AP Managing Partner 421 E Huntington Drive Monrovia, CA 91016 P: +1 213.212.9860 E: kevin.keyfauver@atce.com

One Post Street, No. 2200 San Francisco, CA 94104 P: +1 415.403.3000 E: elizabeth.monti@atce.com

Ventura, California Vince Tarango, IES, IALD Managing Director 973 E. Front Street Ventura, CA 93001 P: +1 805.453.3565 E: vince.Tarango@atce.com Atlanta Georgia Amber Welsh, PE, MS, LEED AP Principal 397 5 th Street NE Atlanta, GA T: +1 678.488.1967 E: amber.welsh@atce.com

Monrovia, California Paul Artelles Principal, Business Development SoCal

421 E Huntington Drive Monrovia, CA 91016 P: +1 213.212.9860 E: paul.artelles@atce.com

San Diego, California Gerald (Jerry) D. Hartford, Jr. PE, LEED AP Managing Director 16885 Via Del Campo, Suite 212 San Diego, CA 92127 T: +1 619.810.7400 E: gerald.hartford@atce.com

ALFATECH